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针对成人酒精使用障碍患者暴饮暴食的靶向葛根治疗:一项二期随机试验。

Targeted Use of Kudzu for Binge Drinking Among Adults With Alcohol Use Disorder: A Phase 2b Randomized Trial.
Santos GM、Coffin P、Dunham A · The American journal of psychiatry · 2026-11-03

研究信息

期刊 / 来源
The American journal of psychiatry
发表日期
2026-11-03
文献库
PubMed
作者
Santos GM, Coffin P, Dunham A
DOI
10.1176/appi.ajp.20251354
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英文原文摘要全文

The aim of this study was to determine the efficacy and acceptability of targeted use of kudzu, an herbal supplement, in adults with alcohol use disorder (AUD) who binge drink. In a double-blind placebo-controlled trial, 120 adults with AUD who binge drink were randomized in a 1:1 ratio to targeted (as-needed) use of oral kudzu extract (2 grams taken on days when binge drinking was anticipated) or matching placebo, plus weekly counseling for 12 weeks. The primary outcome was number of binge-drinking days in the past week. Prespecified secondary outcomes included number of self-reported binge-d

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