更年期过渡期间的睡眠症状、生殖激素与治疗轨迹：两项观察性队列的研究分析

Study objectives Sleep disturbance is common during the menopausal transition, but whether menopausal context is associated with the pace of improvement during insomnia treatment is unclear. We first examined associations of menopausal stage and reproductive-hormone variation with sleep symptoms in a community cohort, and then sleep-quality trajectories during routine insomnia treatment across estimated menopausal proxy groups in a clinical cohort. Methods Two observational cohorts were analysed separately. The Study of Women’s Health Across the Nation (SWAN) included 3,280 women and 22,925 pe