青少年大脑与认知发展（ABCD）研究中外部行为多基因风险的全表型关联研究

Externalizing disorders encompass a range of disinhibited behaviors that typically manifest in youth and are linked with adverse psychological and social outcomes. Polygenic liability to externalizing behaviors has been associated with psychiatric and disease phenotypes in adults. Identifying correlates of genetic risk in youth-prior to the emergence of more impairing manifestations of externalizing behaviors (e.g. substance use disorders)-could improve our etiological understanding and inform targeted prevention efforts. We conducted a phenome-wide association study (PheWAS) to test whether e