使用A型肉毒杆菌毒素、分次二氧化碳激光和局部硅胶的多模式疤痕预防：一项随机分割疤痕临床试验。

Scar formation is a common consequence of surgical and traumatic wounds. Although botulinum toxin Type A (BTX-A), fractional CO2 laser (fCO2L), and topical silicone cream (TSC) are widely used for scar modulation, evidence regarding their combined use remains limited. The aim of the study was to evaluate combined BTX-A, fCO2L, and TSC compared with BTX-A+TSC, fCO2L+TSC, and TSC alone using a randomized split-scar design. Thirty-six patients with head and neck wounds were enrolled in an assessor-blinded, randomized split-scar trial. Each scar half received either combination therapy (BTX-A+fCO2