活动受限慢性疼痛个体中生理睡眠与次日疼痛强度之间的时序关联：一项夜间在家耳EEG睡眠监测研究

Chronic pain and sleep disturbances frequently co-occur. However, most prior research relies on self-report or actigraphy, which reflect behavioural aspects of sleep but provide only limited insight into the underlying sleep physiology. In this pre-registered prospective observational study (NCT06368531), we investigated within-person night-to-night variability in physiological sleep metrics and explored temporal associations between sleep metrics and next-day pain. Individuals with bothersome (n = 4) or high-impact (n = 15) chronic pain completed between 11 and 33 nights of at-home sleep moni