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评估妊娠年龄、妊娠次数和辅助生殖使用对流产中性取向差异中介作用的评估:四项国家级队列研究

Assessing mediation of sexual orientation disparities in miscarriage by age at pregnancy, gravidity, and use of medically assisted reproduction in four national cohorts
Payal Chakraborty、Colleen A. Reynolds、Isa Berzansky · American Journal of Epidemiology · 2026-11-05

研究信息

期刊 / 来源
American Journal of Epidemiology
发表日期
2026-11-05
文献库
OpenAlex
作者
Payal Chakraborty, Colleen A. Reynolds, Isa Berzansky
DOI
10.1093/aje/kwag290
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英文原文摘要全文

Recent research has documented a higher miscarriage risk among sexual minority individuals than heterosexual individuals. These disparities may be partly mediated by age at pregnancy, gravidity, and use of medically assisted reproduction (MAR). We used data from four cohorts (Nurses' Health Study 2 and 3, Growing Up Today Study, and National Longitudinal Study of Adolescent to Adult Health) to estimate randomized interventional analogues of mediational direct and indirect effects of sexual orientation on miscarriage (pure natural direct effects [rPNDE], total natural indirect effects [rTNIE],

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