儿童逆境与自我报告的类风湿关节炎：加拿大老龄化纵向研究的结构方程建模分析

Objective The purpose of this study was to examine the association between adverse childhood experiences (ACEs) and self-reported rheumatoid arthritis (RA), and to investigate potential psychosocial and behavioural mediators of this relationship. Methods Exploratory and confirmatory factor analyses (EFA; CFA) were conducted to assess the dimensionality of ACEs. Hypothesized direct and indirect pathways from a latent ACEs construct to RA were tested using structural equation modeling (SEM) with data (N = 44,142) from the Canadian Longitudinal Study on Aging. Putative mediation through depressio