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在伴有持续性听觉幻觉的精神分裂症患者中,左小脑连续theta burst刺激后临床和功能连接的变化:一项探索性开放标签研究

Clinical and functional connectivity changes following left cerebellar continuous theta burst stimulation in schizophrenia with persistent auditory verbal hallucinations: An exploratory open-label study.
Ou Y、Zhang Y、Ding Y · Psychological medicine · 2026-11-05

研究信息

期刊 / 来源
Psychological medicine
发表日期
2026-11-05
文献库
PubMed
作者
Ou Y, Zhang Y, Ding Y
DOI
10.1017/S0033291726106497
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英文原文摘要全文

Persistent auditory verbal hallucinations (p-AVH) in schizophrenia are often resistant to treatment and linked to dysconnectivity within the cortical-cerebellar-subcortical network. This study investigated whether continuous theta burst stimulation (cTBS) over the left cerebellum alleviates p-AVH and whether treatment-related functional connectivity (FC) changes predict symptom improvement. Thirty schizophrenia patients with p-AVH received 14-days of left cerebellar cTBS. Whole-brain FC changes (post- vs. pretreatment) were used as neuroimaging features, and the reduction rate of PSYRATS-AH (R

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