成人唐氏综合症随机对照试验的招募与保留

Background: Adults with Down Syndrome (DS) face significant health inequalities. Evidence from high-quality randomised controlled trials (RCTs) for interventions are lacking, and there is a perceived difficulty regarding recruiting and retaining participants with DS. Aims: This systematic review aimed to examine planned vs. actual recruitment and retention rates of RCTs involving adults with DS, summarising reported facilitators of and barriers to participation. Method: MEDLINE, PsycINFO, and EMBASE databases were searched systematically to retrieve RCTs of any intervention involving adults wi