从Mimosa tenuiflora(Willd.)Poir提取的一种富含致幻的碱性分数能够减轻C57BL/6小鼠纳洛酮诱发的吗啡戒断症状中的躯体和情感症状。
研究信息
- 期刊 / 来源
- Journal of ethnopharmacology
- 发表日期
- 2026-11-02
- 文献库
- PubMed
- 作者
- da Silva TR, Machado KLB, Carvalho IMM
- DOI
- 10.1016/j.jep.2026.122602
英文原文摘要全文
Mimosa tenuiflora (Willd.) Poir. root bark is traditionally used in northeastern Brazil to prepare "Jurema wine", a beverage employed to relieve emotional distress and restore psychological well-being. However, validating its traditional preparations in central substance withdrawal states remains underexplored. To evaluate the ethnopharmacological potential of M. tenuiflora, we investigated the effects of an alkaloid fraction (AF II) from its root bark on somatic and affective morphine withdrawal symptoms in mice, without compromising analgesia. Male C57BL/6 mice were used for the tests. Possi
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