Family Risk and Resilience Patterns Differentiate Early Childhood Vulnerability to Intergenerational Transmission of Abdominal Pain.

Children are at increased risk of developing chronic abdominal pain if a parent has an abdominal pain-related disorder of brain-gut interaction such as irritable bowel syndrome, suggesting family mechanisms of intergenerational pain transmission. However, patterns of family risk and resilience factors that predict children's vulnerability for developing chronic abdominal pain remain unknown. In a sample of parents with an abdominal pain-related disorder of brain-gut interaction and their young child without chronic pain, this cross-sectional study identified subgroups representing different co