Polygenic dissection of suicidal thoughts and behaviours in high-risk mood-disorder cohorts
Zuriel Ceja、Luis M. García‐Marín、Ian Bernard Hickie · Molecular Psychiatry · 2026-10-30
在高风险心境障碍队列中做多基因分析，区分自杀意念、自杀尝试与自杀死亡的不同遗传贡献。
这篇论文暂时没有中文摘要，下面保留英文原题与摘要。
研究信息
- 期刊 / 来源
- Molecular Psychiatry
- 发表日期
- 2026-10-30
- 文献库
- OpenAlex
- 作者
- Zuriel Ceja, Luis M. García‐Marín, Ian Bernard Hickie
- DOI
- 10.1038/s41380-026-03952-2
英文原文摘要全文
Suicidal thoughts and behaviours (STB) span ideation (SI), attempt (SA), and death (SD), yet the factors distinguishing ideation from attempt remain poorly understood. Genome-wide studies suggest shared yet partially distinct genetic liabilities. However, few analyses have tested the differential contributions of SI-, SA-, and SD-related genetic liability across STB phenotypes, particularly in high-risk mood-disorder populations. We analysed up to 17,622 participants from the Australian Genetics of Depression Study and the Australian Genetics of Bipolar Disorder study, jointly modelling polyge
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